Recherche uO, le dépôt numérique de l'Université d'Ottawa, réunit le matériel de recherche et d'enseignement créé par notre communauté universitaire et nos partenaires. Le savoir de l'Université est ainsi disponible à long terme et en accès libre, ce qui lui procure de la visibilité et facilite sa diffusion.
Communautés dans DSpace
Sélectionner une communauté pour parcourir les collections sous-jacentes.
Nouveaux dépôts
Type d'Item : Item , InGaAsP-on-Insulator Platform for Nonlinear Photonic Applications: Design, Fabrication, and Challenges(Université d'Ottawa / University of Ottawa, 2026-07-15) Mahjoub, Rania; Dolgaleva, KseniaIntegrated photonics has emerged as a promising technology for realizing compact, high speed, and energy-efficient optical systems for applications including optical communications, nonlinear signal processing, and photonic computing. Among the available integrated photonic material platforms, III–V semiconductors are particularly attractive because of their direct bandgap properties, strong optical nonlinearities, and capability for integrating active and passive photonic devices on a single chip. In particular, indium gallium arsenide phosphide (InGaAsP) offers tunable bandgap engineering and compatibility with operation near telecommunication wavelengths, making it a promising candidate for nonlinear integrated photonics. This thesis investigates the development of an InGaAsP-on-insulator (InGaAsP-OI) platform through heterogeneous integration using benzocyclobutene (BCB) adhesive wafer bonding. The work addresses both fabrication challenges and nonlinear waveguide design for two distinct nonlinear processes at telecommunications-relevant wavelengths. The fabrication process includes SiO₂ deposition, BCB bonding, substrate transfer, selective wet etching, and structural characterization of the bonded platform. Particular attention is given to fabrication-induced limitations affecting the reliability and optical performance of the InGaAsP-OI platform. Experimental characterization using scanning electron microscopy (SEM), atomic force microscopy (AFM), and energy-dispersive X-ray spectroscopy (EDX) is used to investigate surface roughness, bonding quality, interfacial defects, and delamination mechanisms associated with the BCB/SiO₂ interface. In addition, nonlinear InGaAsP-OI waveguides are designed and analyzed numerically for two complementary processes. First, dispersion-engineered waveguides for four-wave mixing (FWM) are optimized using Lumerical MODE simulations, achieving a zero-dispersion wavelength of 1553 nm and a nonlinear coefficient of γ ≈ 36.9 W⁻¹m⁻¹ for the optimized geometry (w = 830 nm, h = 800 nm). Second, modal phase-matching-based second-harmonic generation (SHG) is investigated at a fundamental wavelength of 2.6 µm, exploiting the non-centrosymmetric zinc-blende crystal structure of InGaAsP to achieve χ⁽²⁾-based frequency conversion without additional quasi-phase-matching structures. A phase-matched waveguide geometry is identified through analytical mode simulations, and the modal overlap and SHG conversion efficiency are quantified. The results demonstrate the potential of InGaAsP-OI structures for compact, chip-scale nonlinear photonic circuits operating at telecommunications wavelengths, while highlighting the critical role of fabrication optimization and bonding reliability in the development of practical III–V-on-insulator nonlinear photonic platforms.Type d'Item : Item , Distribution and Neighbourhood Deprivation Patterns of Unintentional Home Injuries in British Columbia, Canada(Université d'Ottawa / University of Ottawa, 2026-07-15) Khudadad, Umerdad; Giles, Audrey R.; Pike, IanUnintentional injuries occurring in the home represent a substantial and persistent public health burden in Canada, accounting for a large proportion of injury-related hospitalizations, particularly among older adults, children, and equity-owed populations. While prior research has documented socioeconomic gradients in injury risk, limited scholarship has examined unintentional home injuries through population-level analyses of neighbourhood deprivation, spatial epidemiology, and community-engaged qualitative inquiry to understand how structural inequities and lived experiences intersect to shape vulnerability to home injury risks. Recent immigrants and refugees, particularly those navigating resettlement within constrained housing and settlement structures, remain underrepresented in this body of work. In this manuscript-based thesis, I explored unintentional home injuries in British Columbia (BC) through three stand-alone papers that collectively link structural and spatial patterns of home injury risks and how these risks are experienced by members of Afghan newcomer communities. In the first paper, I examined neighbourhood-level disparities in unintentional home injury hospitalizations across BC between 2015 and 2019 using administrative health data linked with the Canadian Index of Multiple Deprivation (CIMD). I calculated neighbourhood-level unintentional home injury hospitalization rates across CIMD dimensions and observed that injury rates were disproportionately higher in areas characterized by greater situational vulnerability, economic dependency, and residential instability, while lower rates were observed in neighbourhoods with higher ethnocultural diversity. Building on the findings of the first paper, in the second paper, I applied spatial epidemiological methods to identify geographic hotspots of age-standardized unintentional home injury hospitalization rates across BC. Using hotspot analysis and geographically weighted regression, I identified significant spatial clustering of home injury risk, with high-risk areas concentrated in the Lower Mainland. Key predictors of elevated unintentional home injury rates included lower educational attainment, lower annual household income, and higher concentrations of low-rise apartment dwellings, with relationships varying across geographic space. These patterns often characterize neighbourhoods where newcomer populations are more likely to reside. Building on the spatial identification of structurally patterned home injury risk, in the third paper, I examined how these conditions are experienced and navigated by Afghan newcomers in the Greater Vancouver area. Guided by an intersectional framework and community-based participatory research approach, I conducted nine qualitative interviews and a focus group (n=8). Using reflexive thematic analysis, I produced four themes illustrating home safety as a socially negotiated process shaped by vulnerability to unintentional injury risks within structurally constrained and resettlement contexts, and by resilience expressed through collective problem-solving, embodied learning, and community support. Across the three papers, I demonstrated that unintentional home injury risk in BC is patterned across neighbourhood deprivation and geographic space, and that these place-based risks are experienced and navigated within everyday home environments shaped by resettlement conditions. By integrating spatial epidemiology with community-engaged qualitative research, this work advances injury prevention scholarship and calls for equity-driven, place-based, and culturally responsive interventions that address social and structural determinants of home injury risks.Type d'Item : Item , Integration as Translation: Academic Hosts and Migrant Academics in the UK, the US and Canada(Université d'Ottawa / University of Ottawa, 2026-07-15) Ashqar, Amani; Basalamah, SalahThis thesis conceptualizes the academic integration course of permanent and long-term migrant academics in higher education institutions in the United Kingdom, the United States, and Canada as a macro-social translational process constituted through interacting micro-level socially grounded self-translational events. It critiques transfer-centred paradigms within Translation Studies that frame migration primarily in terms of movement and material reconfiguration, arguing that translation must also be theorized as a process of relational and affective transformation. It further argues that academic integration is not the outcome of regulatory reform and individual adaptation but the patterned (re)articulation of unevenly distributed acts of institutional and migrant self-translation unfolding over time. Methodologically, the study adopts a hypothetico-deductive approach (Chesterman, 2017) and analyzes twenty published personal narratives of first-generation migrant academics alongside secondary sources in higher education and migration studies. The empirical chapters demonstrate that academic hosts engage in institutional self-translation primarily through modulation of merit criteria, diversity language, and recruitment frameworks, thereby expanding formal access while retaining interpretive authority over academic recognition. On the other side, migrant academics undertake continuous and multidimensional self-translations across linguistic, epistemic, pedagogical, and affective domains in order to sustain intelligibility within evaluative environments marked by unequal authority. This asymmetry produces a translation mismatch: access to academic positions is granted, yet mutual intelligibility, recognition and belonging remain fragile. The discussion mobilizes the concept of “social translation” (Basalamah, 2022, 2025) to reframe integration as a shared ethical process grounded in responsibility, reciprocity, and the provisional emergence of a regulated frame of reference. However, while social translation articulates the ethical and political conditions of shared mediation, the analysis shows that it does not explicitly theorize how translational duration is differentially lived and sustained across asymmetrical positions. The thesis therefore advances the concept of translational labour - genealogically anchored in Ricœur's (2006) notion of labour - to name the cumulative cognitive, affective, and temporal effort required to sustain intelligibility once access has been achieved. Translational labour renders visible how social translation is unevenly borne across institutional and migrant positions, and how fatigue, withdrawal, or suspension function as translational signals rather than failures. By articulating academic integration as macro-translation constituted through interacting micro-translational events, and by theorizing translational labour as the experiential register of translational duration, the study extends Translation Studies beyond interlingual transfer into the analysis of coexistence within (academic) institutions. It offers a framework for examining how translation operates as the constitutive condition of integration within heterogeneous academic societies and clarifies the ethical and sustainability conditions under which social translation may remain viable over time.Type d'Item : Item , Elucidating the Immunomodulatory Properties of Small Extracellular Vesicles Derived from SMAC Mimetic Treated Cancer Cells(Université d'Ottawa / University of Ottawa, 2026-07-15) Yin, Jordan Jiaxi; Beug, Shawn T.Several members of the Inhibitor of Apoptosis (IAP) proteins act as potent anti-apoptotic factors and as key negative regulators of the alternative NF-κB pathway, thereby regulating pro-inflammatory and immune responses. SMAC mimetics (SMs) are a class of drugs designed to antagonize the IAPs, enabling promotion of cell death and stimulation of immune activation. Over the past decade, small extracellular vesicles (sEVs) have gained attention in cancer immunotherapy due to their role in intercellular communication and molecular cargo transfer. This study investigates whether SMs can enhance anti-tumor immune responses mediated by antigen-presenting sEVs. sEVs were isolated from two ovalbumin (OVA)-expressing murine cancer cells, B16F10-OVA and MC38-OVA. The sEVs were characterized using latest MISEV guidelines, such as particle sizing and quantitation, as well as assessment of canonical vesicle-associated markers. The functional capabilities of these sEVs were then evaluated in dendritic cell (DC) co-culture systems to determine their capacity to modulate DC activation, maturation, and antigen presentation. Downstream effects on CD8⁺ T cell responses were assessed using OT-I T cells as a model of recognizing the OVA-specific priming and activation. My findings support a model in which SMs alter tumour sEV release and immune cell activation. These tumour-derived sEVs alongside with SMs promoted DC activation and OVA antigen presentation. Further, the uptake of tumour-derived sEVs within DCs led to activation of antigen-specific CD8⁺ T cells, supporting the role of sEV-mediated transfer of both peptide- and immune-relevant signals. Overall, this work identifies how SMs influence adaptive immunity through the context of sEVs. These findings establish a foundation for further investigation into sEV-mediated mechanisms of anti-tumour immunity and support the therapeutic potential of combining SMs with immune-based strategies in cancer.Type d'Item : Item , On Cross-Domain Security Architecture for MQTT-SN in Constrained IoT Systems(Université d'Ottawa | University of Ottawa, 2026-07-14) Gupta, Hemant; Nayak, AmiyaThe rapid growth of limited Internet of Things (IoT) devices has made it even more important to have lightweight, reliable, and secure communication protocols that can operate in environments with limited processing power, memory, and energy. MQTT-SN is a version of MQTT that works with sensor networks that do not use IP. It has a good publish-subscribe model, but lacks key security features, making IoT applications vulner- able. MQTT-SN inherits almost all the properties and features of MQTT, along with its vulnerabilities, and the MQTT-SN specification does not specify how to address the security requirements of MQTT-SN components. This gap drives a thorough examination of MQTT-SN’s security in real-world deployments critical to safety and privacy. This thesis introduces a cohesive security framework for MQTT-SN, formulated and corroborated within three illustrative IoT domains: Vehicle-to-Vehicle and Vehicle-to-Emergency-Services (V2S) communication, smart lock systems, and continuous glucose monitoring (CGM) healthcare devices. The thesis presents an adapted SREP/SQUARE methodology specifically designed for IoT ecosystems, facilitating the systematic identification of assets, threats, and security requirements. This framework is utilized for all three use cases, generating comprehensive threat models and prioritized security requirements that account for the limitations and risks associated with constrained devices and publish-subscribe architectures. Later, the thesis presents comprehensive security architectures for V2S, smart lock, and CGM systems. These include protocols for onboarding, key establishment, message protection, and access control, in detail. We use Scyther for formal verification, timing and energy analysis on limited hardware, and comparisons with existing technologies and commercial products to test these architectures. The results show that the proposed designs offer strong authentication, privacy, integrity, authorization, and replay protection. This work improves the security of IoT communication by providing the first complete, cross-domain security architecture for MQTT-SN. It shows that MQTT-SN can be a strong, scalable, and efficient way for different IoT applications to communicate, as long as it is properly secured. These applications can include smart homes, healthcare, and vehicle safety systems.