Recherche uO, le dépôt numérique de l'Université d'Ottawa, réunit le matériel de recherche et d'enseignement créé par notre communauté universitaire et nos partenaires. Le savoir de l'Université est ainsi disponible à long terme et en accès libre, ce qui lui procure de la visibilité et facilite sa diffusion.

Nouveaux dépôts

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    Horizons Impact: A Quantitative Analysis of Reach, Engagement, and Readiness
    (2026) Mitsou, Marie
    This report presents a quantitative analysis of the Horizons Career Development Program at the University of Ottawa. Horizons is a bilingual digital career development program managed by Career Development and Experiential Learning (CDEL) and integrated with Career Corner services. The analysis draws on engagement, awards, and Career Readiness Quiz data from launch in January 2024 through April 30, 2026. Three layers of evidence are reported: program reach, including access, active engagement, and engagement depth; multi-year companion engagement, demonstrating that students access Horizons across multiple academic years as the program's design intends; and readiness change, measured through the My Vocational Situation (MVS) instrument among students who took the quiz more than once. The findings show that Horizons has reached 13,680 students cumulatively, with 5,827 actively entering and 3,489 engaging with content beyond the quiz entry point. Year-over-year growth is significant across every layer of the funnel. A clear dose-response is observed: students who engage at greater depth show larger and more consistent readiness gains. Engaged students gained an average of 18.7 percentage points on the MVS, with an incremental gain of 7.8 percentage points attributable to Horizons. The 26 MVS items touch on dimensions across multiple Career Development Learning Outcomes in CDEL's developmental sequence (Knowing Yourself, Career Identity, Career Confidence, Adaptability, and Skills Literacy), reflecting shared theoretical foundations in career development scholarship and providing quantitative evidence of student movement along the developmental arc that builds toward Career Agency. Five recommendations are offered to strengthen Horizons reach, support sustained student engagement, and continue the program's curricular development. This report is part of CDEL's evidence base for Horizons, alongside the conceptual framework for career development practice and the qualitative thematic analysis of student survey responses.
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    Dans les pas de la Hallyu à Séoul : errances touristiques, appartenances et paysages urbains sous l’empreinte de la commercialisation culturelle
    (Université d'Ottawa | University of Ottawa, 2026-07-28) Dontigny-Charette, Zoé; Stalcup, Meg
    Cette thèse examine les ramifications de la Hallyu à Séoul, un phénomène culturel rendu possible par la commercialisation concertée de la culture sud-coréenne amorcée dans les années 1990. En analysant les politiques publiques et les stratégies coordonnées entre l’État, les agences culturelles et l’industrie du divertissement, elle met en lumière la manière dont ces acteurs ont orienté la production, la visibilité et la circulation des contenus culturels. À partir d’un terrain mené dans les districts de Gangnam et Mapo-gu, combinant visites guidées touristiques, flâneries inspirées du concept du flâneur urbain et quatre entretiens préliminaires, dix entrevues semi-dirigées et quatre non dirigées, cette recherche explore comment la Hallyu reconfigure les espaces urbains, les pratiques quotidiennes et les formes d’appartenance. Les résultats montrent que l’industrie touristique constitue un vecteur central de cette commercialisation culturelle : de nombreuses infrastructures, activités et mises en scène urbaines ont été adaptées pour répondre aux attentes des fans internationaux. Le paysage urbain, quant à lui, traduit visuellement les ramifications de la Hallyu à travers des manifestations matérielles et symboliques (panneaux publicitaires, cafés thématiques, boutiques spécialisées) qui fonctionnent comme des archives vivantes de ce phénomène. Toutefois, l’étude révèle également les ambivalences de cette commercialisation, notamment chez les jeunes Sud-Coréens confrontés à une hypercompétitivité et à des normes sociales strictes. En mettant en lumière ces dynamiques, cette thèse contribue à une compréhension nuancée de la Hallyu comme phénomène culturel complexe, façonnant simultanément les espaces, les imaginaires et les subjectivités dans la Séoul contemporaine.
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    The Metaproteomics Initiative: five years of community-driven progress
    (2026-07-23) Van Den Bossche, Tim; Grenga, Lucia; Alves, Gelio; Arntzen, Magnus Ø.; Benndorf, Dirk; Brauer, Madita; Figeys, Daniel; Henry, Celine; Hettich, Robert L.; Heyer, Robert; Jagtap, Pratik D.; Jehmlich, Nico; Kleiner, Manuel; Li, Leyuan; Mesuere, Bart; Pabst, Martin; Pandhal, Jagroop; Pope, Phillip B.; Seifert, Jana; Trautwein-Schult, Anke; Verschaffelt, Pieter; Wilmes, Paul; Armengaud, Jean; Kunath, Benoit J.
    Abstract The Metaproteomics Initiative was officially launched in 2021 to strengthen collaboration, promote knowledge exchange, and support and lead standardization efforts within the growing metaproteomics community. Over the past 5 years, the Initiative has developed into a structured, global network of researchers. It has launched community-driven benchmark studies, helped shape emerging metadata and reporting standards, developed practical guidance and training materials, organized international symposia, and fostered connections across the microbiome research landscape ( https://metaproteomics.org/ ). We outline the Initiative’s organization, activities, achievements, and ongoing efforts, and reflect on how sustained, community-led coordination has shaped the development of metaproteomics as a field. We further position the Grand Metaproteome Challenges as a next step toward coordinated, community-scale biological research, aimed at advancing functional microbiome studies across clinical, industrial, and environmental application domains, and invite engagement from the wider microbiome and omics communities. Video Abstract
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    The need for standardization and improved open (meta)data practices in metaproteomics
    (2026-07-23) Van Den Bossche, Tim; Wolf, Maximilian; Armengaud, Jean; Arntzen, Magnus Ø.; Benndorf, Dirk; Figeys, Daniel; Grenga, Lucia; Hettich, Robert L.; John, Nithu S.; Jagtap, Pratik; Jehmlich, Nico; Kleiner, Manuel; Kunath, Benoit J.; Li, Leyuan; Lipton, Mary; Mesuere, Bart; Neely, Benjamin A.; Ning, Zhibin; Pedersen, Ane L.; Perez-Riverol, Yasset; Rajan, Jeena; Schallert, Kay; Seifert, Jana; Uzzau, Sergio; Verschaffelt, Pieter; Wilmes, Paul; Vizcaíno, Juan A.; Martens, Lennart; Heyer, Robert
    Abstract Metaproteomics enables functional insight into microbial communities by identifying and quantifying proteins in complex samples. Yet, heterogeneous analytical workflows and the lack of standardization across experimental and bioinformatics stages hinder reproducibility and comparability, limiting integration with other omics data. We here present a community-developed reporting checklist tailored to the specific needs of metaproteomics. We also outline current efforts to enable structured and interoperable metadata capture, drawing on standards from proteomics and microbiome research wherever possible. By promoting transparent reporting and advancing metadata practices, our recommendations aim to align metaproteomics more closely with FAIR principles and support reproducible and interoperable research practices. Video Abstract
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    Fully automatic left ventricle segmentation in $$^{82}$$ Rb PET/CT Using a semi-supervised nnU-net
    (2026-05-28) Amirian, Mohammadreza; Chevalley, Arthur; Asiain, María M.; Klein, Ran; DeKemp, Robert; Moulton, Eric; Prior, John O.; Kamani, Christel H.; Jreige, Mario; Depeursinge, Adrien
    Abstract Background Quantification of myocardial blood flow (MBF) with $$^{82}$$ Rb PET/CT requires accurate delineation of the left ventricle (LV). Manual or semi-automated contouring remains time-consuming and error-prone, particularly in hypoperfused myocardium. We developed and validated a fully automatic LV segmentation pipeline using nnU-Net applied to $$^{82}$$ Rb PET/CT. A manual, multimodal segmentation protocol integrating dynamic PET and CT was established in a single-center cohort of 40 non-gated PET/CT series (20 patients, rest & stress), including challenging cases with extensive necrosis (median 21%). The resulting ground truth masks were used for five-fold cross-validation, and semi-supervised learning incorporated 805 additional unlabeled dynamic PET series (504 patients). Model performance was compared with an optimized semi-automatic thresholding baseline (35% $$\text {SUV}_{\text {max}}$$ ). Results The nnU-Net significantly outperformed the baseline, achieving a mean Dice of 87.8[85.6, 89.2]% vs 75.1[72.9, 76.9]%, recall 89.1[86.1, 91.4]% vs 82.6[79.1, 85.4]%, and precision 88.1[84.2, 90.4]% vs 70.2[67.2, 73.0]%. The improvement was most pronounced in hypoperfused regions, where recall increased by 20–30% compared to thresholding. Semi-supervised learning modestly enhanced model robustness across both rest and stress acquisitions. Conclusions A deep-learning-based approach enables fully automatic LV segmentation in $$^{82}$$ Rb PET/CT with near-expert accuracy. This framework eliminates manual interaction, supports large-scale MBF quantification, and paves the way for reproducible, high-throughput cardiac PET analysis in clinical and research workflows.