Interrupted aza-Wittig reactions using iminophosphoranes to synthesize 11C-carbonyls

dc.contributor.author	Ismailani, Uzair S
dc.contributor.author	Munch, Maxime
dc.contributor.author	Mair, Braeden A
dc.contributor.author	Rotstein, Benjamin H
dc.date.accessioned	2022-08-26T21:02:56Z
dc.date.available	2022-08-27T09:00:12Z
dc.date.issued	2021
dc.description.abstract	A direct CO2-fixation methodology couples structurally diverse iminophosphoranes with various nucleophiles to synthesize ureas, carbamates, thiocarbamates, and amides, and is amenable for 11C radiolabeling. This methodology is practical, as demonstrated by the synthesis of >35 products and isolation of the molecular imaging radiopharmaceuticals [11C]URB694 and [11C]glibenclamide.	en_US
dc.embargo.terms	2022-05-04
dc.identifier.doi	10.1039/d1cc01016f	en_US
dc.identifier.uri	http://pubs.rsc.org/en/content/articlelanding/2021/cc/d1cc01016f	en_US
dc.identifier.uri	http://hdl.handle.net/10393/43963
dc.identifier.uri	https://doi.org/10.20381/ruor-28176
dc.language.iso	en	en_US
dc.rights	Attribution-NonCommercial-NoDerivatives 4.0 International	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/4.0/	*
dc.title	Interrupted aza-Wittig reactions using iminophosphoranes to synthesize 11C-carbonyls	en_US
dc.type	Article	en_US