Repository logo

Cognitive and Associated Communication Impairments Following Unilateral Acute Ischemic Stroke: Frequency, Predictors, and Clinical Outcomes

dc.contributor.authorHour, Povkannika
dc.contributor.supervisorFlowers, Heather
dc.contributor.supervisorSteffener, Jason
dc.date.accessioned2023-01-17T19:21:56Z
dc.date.issued2023-01-17en_US
dc.description.abstractBackground: Cognitive-communication disorders are preferentially associated with right hemisphere brain lesions and can be difficult to identify. Objectives: To identify predictors of cognitive-communication and overarching cognitive impairments in acute ischemic stroke (AIS). Methods: A prior MRI dataset of 72 AIS patients provided the basis for a voxel-based lesionsymptom mapping (VLSM) analysis of post-stroke aphasia and motor speech impairments. A chart review (N=32) of AIS patients was subsequently conducted to identify the frequency and predictors of cognitive and cognitive-communication impairments more comprehensively. Results: The VLSM analyses revealed involvement of the insula for aphasia and motor speech impairments. Frequencies of cognitive and cognitive-communication impairments were 62.5% and 34%, respectively. Predictors of cognitive impairments included left lesion laterality and stroke onset-to-arrival time. Conclusion: We identified the frequency and predictors of poststroke cognitive and cognitive-communication impairments in acute stroke. There is a need for lesion mapping analyses in the future. Contexte: Les troubles cognitivo-linguistiques (TC-L) sont liés aux lésions cérébrales droites et sont difficiles à identifier. Objectifs: Identifier les indicateurs des TC-L après un accident vasculaire cérébrale ischémique aigu (AVC-IA) et des troubles cognitifs (TC). Méthodes: Un échantillon de 72 patients avec AVC-IA a permis une analyse cartographique lésion-symptôme basée sur les voxels (CL-SV) pour l’aphasie et les troubles de la parole (TP). Ensuite, une revue des dossiers (N=32, AVC-IA) a été réalisée pour identifier la fréquence et indicateurs des TC et TC-L. Résultats: Les analyses CL-SV ont démontré une association entre le cortex insulaire et l’aphasie et les TP. La fréquence des TC et TC-L était 62.5% and 34% respectivement. Les indicateurs des TC comprenaient la latéralité gauche et le temps entre l’apparition des symptômes et l’arrivée à l’hôpital. Conclusion: Nous avons identifié la fréquence et indicateurs des TC et TC-L. Il reste une lacune scientifique concernant les analyses CL-SV.
dc.embargo.lift2025-01-17
dc.embargo.terms2025-01-17
dc.identifier.urihttp://hdl.handle.net/10393/44526
dc.identifier.urihttp://dx.doi.org/10.20381/ruor-28732
dc.language.isoenen_US
dc.publisherUniversité d'Ottawa / University of Ottawaen_US
dc.subjectcognitive impairmentsen_US
dc.subjectcognitive-communicationen_US
dc.subjectacute ischemic strokeen_US
dc.subjectacute stroke careen_US
dc.subjectcommunication impairmentsen_US
dc.titleCognitive and Associated Communication Impairments Following Unilateral Acute Ischemic Stroke: Frequency, Predictors, and Clinical Outcomesen_US
dc.typeThesisen_US
thesis.degree.disciplineSciences de la santé / Health Sciencesen_US
thesis.degree.levelMastersen_US
thesis.degree.nameMScen_US
uottawa.departmentSciences interdisciplinaires de la santé / Interdisciplinary Health Sciencesen_US

Files

Original bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail ImageThumbnail Image
Name:
Hour_Povkannika_2023_Thesis.pdf
Size:
3.02 MB
Format:
Adobe Portable Document Format
Description:

License bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail ImageThumbnail Image
Name:
license.txt
Size:
6.65 KB
Format:
Item-specific license agreed upon to submission
Description: