Cognitive and Associated Communication Impairments Following Unilateral Acute Ischemic Stroke: Frequency, Predictors, and Clinical Outcomes
| dc.contributor.author | Hour, Povkannika | |
| dc.contributor.supervisor | Flowers, Heather | |
| dc.contributor.supervisor | Steffener, Jason | |
| dc.date.accessioned | 2023-01-17T19:21:56Z | |
| dc.date.issued | 2023-01-17 | en_US |
| dc.description.abstract | Background: Cognitive-communication disorders are preferentially associated with right hemisphere brain lesions and can be difficult to identify. Objectives: To identify predictors of cognitive-communication and overarching cognitive impairments in acute ischemic stroke (AIS). Methods: A prior MRI dataset of 72 AIS patients provided the basis for a voxel-based lesionsymptom mapping (VLSM) analysis of post-stroke aphasia and motor speech impairments. A chart review (N=32) of AIS patients was subsequently conducted to identify the frequency and predictors of cognitive and cognitive-communication impairments more comprehensively. Results: The VLSM analyses revealed involvement of the insula for aphasia and motor speech impairments. Frequencies of cognitive and cognitive-communication impairments were 62.5% and 34%, respectively. Predictors of cognitive impairments included left lesion laterality and stroke onset-to-arrival time. Conclusion: We identified the frequency and predictors of poststroke cognitive and cognitive-communication impairments in acute stroke. There is a need for lesion mapping analyses in the future. Contexte: Les troubles cognitivo-linguistiques (TC-L) sont liés aux lésions cérébrales droites et sont difficiles à identifier. Objectifs: Identifier les indicateurs des TC-L après un accident vasculaire cérébrale ischémique aigu (AVC-IA) et des troubles cognitifs (TC). Méthodes: Un échantillon de 72 patients avec AVC-IA a permis une analyse cartographique lésion-symptôme basée sur les voxels (CL-SV) pour l’aphasie et les troubles de la parole (TP). Ensuite, une revue des dossiers (N=32, AVC-IA) a été réalisée pour identifier la fréquence et indicateurs des TC et TC-L. Résultats: Les analyses CL-SV ont démontré une association entre le cortex insulaire et l’aphasie et les TP. La fréquence des TC et TC-L était 62.5% and 34% respectivement. Les indicateurs des TC comprenaient la latéralité gauche et le temps entre l’apparition des symptômes et l’arrivée à l’hôpital. Conclusion: Nous avons identifié la fréquence et indicateurs des TC et TC-L. Il reste une lacune scientifique concernant les analyses CL-SV. | |
| dc.embargo.lift | 2025-01-17 | |
| dc.embargo.terms | 2025-01-17 | |
| dc.identifier.uri | http://hdl.handle.net/10393/44526 | |
| dc.identifier.uri | http://dx.doi.org/10.20381/ruor-28732 | |
| dc.language.iso | en | en_US |
| dc.publisher | Université d'Ottawa / University of Ottawa | en_US |
| dc.subject | cognitive impairments | en_US |
| dc.subject | cognitive-communication | en_US |
| dc.subject | acute ischemic stroke | en_US |
| dc.subject | acute stroke care | en_US |
| dc.subject | communication impairments | en_US |
| dc.title | Cognitive and Associated Communication Impairments Following Unilateral Acute Ischemic Stroke: Frequency, Predictors, and Clinical Outcomes | en_US |
| dc.type | Thesis | en_US |
| thesis.degree.discipline | Sciences de la santé / Health Sciences | en_US |
| thesis.degree.level | Masters | en_US |
| thesis.degree.name | MSc | en_US |
| uottawa.department | Sciences interdisciplinaires de la santé / Interdisciplinary Health Sciences | en_US |
