Effects of non-pharmacological interventions on sleep quality in older adults: a systematic review and network meta-analysis of randomized controlled trials

Abstract

Abstract Background Sleep problems are common among older adults and are associated with a wide range of adverse health outcomes. Concerns about pharmacological treatments have increased interest in non-pharmacological interventions; however, evidence comparing their relative effectiveness remains limited. Methods A systematic search was conducted in PubMed, Scopus, Embase, Web of Science, Cochrane Library, and CINAHL. Randomized controlled trials (RCTs) evaluating non-pharmacological interventions in adults aged ≥ 60 years published between 2000 and 2024 were included. Network meta-analyses were conducted using random-effects models to estimate standardized mean differences (SMDs) with 95% confidence intervals (CIs). P-scores were used to rank the efficacy of interventions. The protocol was registered in PROSPERO (CRD42024521492). Results Thirty-four RCTs involving 3078 participants and 21 interventions were included. Eleven interventions significantly improved sleep quality. Cognitive behavioral therapy for insomnia plus positive mood strategies (CBT-I+) showed the largest effect (P-score = 0.99, SMD = − 3.32, 95% CI − 4.59 to − 2.06), followed by cognitive behavioral therapy for insomnia (CBT-I) (P-score = 0.92, SMD = − 2.18, 95% CI − 3.04 to − 1.31). Subgroup analyses indicated that music therapy (MUS) was more effective among participants with PSQI < 10 (SMD = − 1.25, 95% CI − 1.85 to − 0.65), whereas CBT-I+ showed greater effects for those with PSQI ≥ 10 (SMD = − 5.48, 95% CI − 6.80 to − 4.16). By intervention setting, traditional Chinese health-promotion exercise (TCHPE) was more effective in home-based settings (SMD = − 1.55, 95% CI − 2.60 to − 0.50), whereas CBT-I+ showed greater effects in non-home settings (SMD = − 3.31, 95% CI − 4.57 to − 2.06). Conclusions CBT-I+ was associated with the greatest improvements in sleep quality among older adults, particularly those with baseline PSQI ≥ 10 and in non-home settings. MUS showed greater benefits among older adults with baseline PSQI < 10, and TCHPE showed greater benefits in home-based settings. These findings support stratified, context-specific intervention selection. Given the low GRADE certainty, these results should be interpreted with caution.