Biofilm Treatments with Electric Currents

Description
Title: Biofilm Treatments with Electric Currents
Authors: Haddad, Peter Alexander
Date: 2014-04-17
Abstract: The Problem: Biofilms are a community of bacteria that cause infections which are resistant to the immune system and antimicrobial treatments, posing a significant threat for patients with implantable and indwelling medical devices. Purpose: The purpose of this research is to effectively treat biofilms utilizing electric currents assisted by antibiotics. Method: Evaluated the impact of direct electric current with or without vancomycin against Staphylococcus epidermidis biofilms. Results: (1) Electric current reduced the S. epidermidis biofilm and (2) increased the effectiveness of vancomycin. (3) Older biofilms had an increased resistance to vancomycin treatments. (4) Higher electric current intensities and (5) longer duration treatments were more effective against biofilms. Conclusion: Electric current increased the effectiveness of vancomycin against S. epidermidis biofilms.
URL: http://hdl.handle.net/10393/30947
http://dx.doi.org/10.20381/ruor-6499
CollectionThèses, 2011 - // Theses, 2011 -
Files
Haddad_Peter_2014_thesis.pdfThesis2.72 MBAdobe PDFOpen