Discussion of Bisphenol A as an Environmental Endocrine Disruptor: The Low Dose Effect and Governmental Regulations Concerning its Use and Disposal: A Literature Review
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Abstract
The disruptive and potentially harmful effects of naturally occurring and manmade
endocrine disrupting compounds found in the environment are a topic of
considerable debate within government, industry and the general public. Bisphenol
A (BPA) is of particular concern due to its incorporation in many consumer
products and its potential for leeching. Scientific study continues with
attempts to identify and quantify risk associated with this chemical, in order to
support industry and regulatory actions. The issue of greatest concern with regards
to BPA is the effects of routine exposure to very low concentration of the
chemical. The effects of this phenomenon, called Low Dose Effects, raise a great
deal of controversy as it is difficult to accurately assess the health outcomes from
these exposures. This paper gives a basic understanding of what constitutes Low
Dose effects and also examines several studies conducted to determine the
health outcomes as a result of exposure to low dose BPA.
Regulatory activities seek to mitigate risk through enactment of legislation to
control the use of and exposure to these compounds. As a result the regulatory
agencies in Canada and the U.S. have banned the sale of certain consumer products
containing BPA and have imposed strict limits on concentration in industrial
effluents and waste water drainage. This paper outlines the conditions and
limits put in place by both the Canadian and U.S. government regarding the
presence of BPA in effluents and consumer products.
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Keywords
endocrine disruption, male infertility, low dose effect
