Dunn, Crystal R2013-11-072013-11-0720062006Source: Masters Abstracts International, Volume: 45-02, page: 0832.http://hdl.handle.net/10393/27241http://dx.doi.org/10.20381/ruor-11986Objective. To conduct a preliminary exploration of psychological outcomes and health behaviour in individuals undergoing testing for genetic mutations associated with thrombophilia. Methods. Subjects were 57 carriers and 54 non-carriers identified through an existing pilot study. Part I analyzed perceived risk and psychological data collected at baseline, 1 week and 12 months post-test. Part II used a cross-sectional survey to collect data regarding: test implications, perceived causes and control, and behaviour change post-test. Results. Accuracy of risk perception improved post-test due to decreased risk perception among non-carriers. No major psychological harms were identified, but a subgroup of carriers may experience distress. Participants had a high sense of control over their risk of venous thromboembolism and had a good understanding of risk factors. Many tried to change their behaviours post-test, but did not report doing this specifically to reduce their risk of a blood clot. Conclusions. This exploratory study suggests no major psychological harm arising from genetic testing, but its findings need replication with larger samples.175 p.enHealth Sciences, Public Health.Thesis