Clark, Edward G.Vijayan, Anitha2023-03-142023-03-142023-03-08Critical Care. 2023 Mar 08;27(1):88https://doi.org/10.1186/s13054-023-04389-7https://doi.org/10.20381/ruor-28907http://hdl.handle.net/10393/44701Abstract Prolonged Intermittent Renal Replacement Therapy (PIRRT) is the term used to define ‘hybrid’ forms of renal replacement therapy. PIRRT can be provided using an intermittent hemodialysis machine or a continuous renal replacement therapy (CRRT) machine. Treatments are provided for a longer duration than typical intermittent hemodialysis treatments (6–12 h vs. 3–4 h, respectively) but not 24 h per day as is done for continuous renal replacement therapy (CRRT). Usually, PIRRT treatments are provided 4 to 7 times per week. PIRRT is a cost-effective and flexible modality with which to safely provide RRT for critically ill patients. We present a brief review on the use of PIRRT in the ICU with a focus on how we prescribe it in that setting.Journal Article2023-03-14enThe Author(s)