Grant, Alyssa2020-10-022021-10-022020-10-02http://hdl.handle.net/10393/41161http://dx.doi.org/10.20381/ruor-25385Objectives: Our goal was to explore the association between vision with cognitive change scores and incident depression. Methods: A 3-year prospective cohort study was performed. Incident depression was defined using a cut-off score of 10 on the Center for Epidemiologic Studies Depression scale. Cognitive change was examined by calculating the difference between baseline and follow-up cognitive tests scores. Multivariable Poisson and linear regression were used. Results: Cataract was associated with incident depression (relative risk=1.20, 95% confidence interval 1.05, 1.37). Visual impairment was associated with the 3-year change in Rey Auditory Verbal Learning Test (RAVLT) (β=-0.18, 95% CI= -0.28, -0.07), RAVLT-Delayed (β=-0.13, 95% CI= -0.25, -0.02), and Animal Naming Test (β=-0.95, 95% CI= -1.44, -0.45) scores. Glaucoma was associated with 3-year Mental Alternation Test change scores (β=-0.40, 95% CI -0.77, -0.04). Conclusions: Cataract was associated with increased depression risk. VI and glaucoma are associated with 3-year changes in cognitive test scores.enVisual impairmentAge-related eye diseaseCanadian Longitudinal Study on AgingDepressionCognitive declineThesis