Beamish, EricTabard-Cossa, VincentKwok, HaroldGodin, Michel2013-12-052013-12-0520122012Beamish, E.; Kwok, H.; Tabard-Cossa, V.; Godin, M. Nanotechnology 2012, 23, 405301http://hdl.handle.net/10393/30308We present a methodology for preparing silicon nitride nanopores that provides in situ control of size with sub-nanometer precision while simultaneously reducing electrical noise by up to three orders of magnitude through the cyclic application of high electric fields in an aqueous environment. Over 90% of nanopores treated with this technique display desirable noise characteristics and readily exhibit translocation of double-stranded DNA molecules. Furthermore, previously used nanopores with degraded electrical properties can be rejuvenated and used for further single-molecule experimentsenNucleic acidsNanotechnologies-designNanoporeSize controlSolid-stateNoise reductionArticle10.1088/0957-4484/23/40/405301