Integrating nanopore sensors within microfluidic channel arrays using controlled breakdown

dc.contributor.authorTahvildari, Radin
dc.contributor.authorBeamish, Eric
dc.contributor.authorTabard-Cossa, Vincent
dc.contributor.authorGodin, Michel
dc.identifier.citationLab. Chip 2015, 15, 1407-1411
dc.description.abstractNanopore arrays are fabricated by controlled dielectric breakdown (CBD) in solid-state membranes integrated within polydimethylsiloxane (PDMS) microfluidic devices. This technique enables the scalable production of independently addressable nanopores. By confining the electric field within the microfluidic architecture, nanopore fabrication is precisely localized and electrical noise is significantly reduced. Both DNA and protein molecules are detected to validate the performance of this sensing platform.
dc.description.sponsorshipThis work was supported by the Natural Sciences and Engineering Research Council of Canada (NSERC), the Ontario Ministry of Research and Innovation, and the Canada Foundation for Innovation.
dc.titleIntegrating nanopore sensors within microfluidic channel arrays using controlled breakdown
CollectionPhysique // Physics

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