Precise control of the size and noise of solid-state nanopores using high electric fields

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dc.contributor.authorBeamish, Eric
dc.contributor.authorTabard-Cossa, Vincent
dc.contributor.authorKwok, Harold
dc.contributor.authorGodin, Michel
dc.date.accessioned2013-12-05T20:51:52Z
dc.date.available2013-12-05T20:51:52Z
dc.date.created2012
dc.date.issued2012
dc.identifier.citationBeamish, E.; Kwok, H.; Tabard-Cossa, V.; Godin, M. Nanotechnology 2012, 23, 405301
dc.identifier.urihttp://hdl.handle.net/10393/30308
dc.description.abstractWe present a methodology for preparing silicon nitride nanopores that provides in situ control of size with sub-nanometer precision while simultaneously reducing electrical noise by up to three orders of magnitude through the cyclic application of high electric fields in an aqueous environment. Over 90% of nanopores treated with this technique display desirable noise characteristics and readily exhibit translocation of double-stranded DNA molecules. Furthermore, previously used nanopores with degraded electrical properties can be rejuvenated and used for further single-molecule experiments
dc.description.sponsorshipNatural Sciences and Engineering Research Council of Canada, Canada Foundation for Innovation, Ontario Research Fund
dc.language.isoen
dc.subjectNucleic acids
dc.subjectNanotechnologies-design
dc.subjectNanopore
dc.subjectSize control
dc.subjectSolid-state
dc.subjectNoise reduction
dc.titlePrecise control of the size and noise of solid-state nanopores using high electric fields
dc.typeArticle
dc.identifier.doi10.1088/0957-4484/23/40/405301
CollectionPhysique // Physics

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