Precise control of the size and noise of solid-state nanopores using high electric fields

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Title: Precise control of the size and noise of solid-state nanopores using high electric fields
Authors: Beamish, Eric
Tabard-Cossa, Vincent
Kwok, Harold
Godin, Michel
Date: 2012
Abstract: We present a methodology for preparing silicon nitride nanopores that provides in situ control of size with sub-nanometer precision while simultaneously reducing electrical noise by up to three orders of magnitude through the cyclic application of high electric fields in an aqueous environment. Over 90% of nanopores treated with this technique display desirable noise characteristics and readily exhibit translocation of double-stranded DNA molecules. Furthermore, previously used nanopores with degraded electrical properties can be rejuvenated and used for further single-molecule experiments
URL: http://hdl.handle.net/10393/30308
DOI: 10.1088/0957-4484/23/40/405301
CollectionPhysique // Physics
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