Clinical Prediction Rule for the Development of New Onset Postoperative Atrial Fibrillation After Cardiac Surgery

FieldValue
dc.contributor.authorTran, Diem
dc.date.accessioned2013-08-13T19:52:41Z
dc.date.available2013-08-13T19:52:41Z
dc.date.created2013
dc.date.issued2013
dc.identifier.urihttp://hdl.handle.net/10393/24400
dc.identifier.urihttp://dx.doi.org/10.20381/ruor-3153
dc.description.abstractThis project set out to derive a prediction rule based on preoperative clinical variables to identify patients with high risk of developing atrial fibrillation following cardiac surgery. Methods: Prospectively collected data from a perioperative database was corroborated with chart review to identify eligible patients who had non-emergent surgery in 2010. Details on 28 preoperative variables were collected and significant predictors (p<0.2) were inserted into multivariable logistic regression and recursive partitioning. Results: 305 (30.5%) of 999 patients developed new onset postoperative atrial fibrillation. Eleven variables were significantly associated with atrial fibrillation, however, both final models included only three: left atrial dilatation, mitral valve disease and age. Bootstrapping with 5000 samples confirmed that both final models provide consistent predictions. Coefficients from the logistic regression model were converted into a simple seven point predictive score. Conclusions: This simple risk score can identify patients at higher risk of developing atrial fibrillation after cardiac surgery.
dc.language.isoen
dc.publisherUniversité d'Ottawa / University of Ottawa
dc.subjectatrial fibrillation
dc.subjectpostoperative complications
dc.subjectcardiac surgery
dc.subjectclinical prediction rule
dc.titleClinical Prediction Rule for the Development of New Onset Postoperative Atrial Fibrillation After Cardiac Surgery
dc.typeThesis
dc.faculty.departmentÉpidémiologie et médecine sociale / Epidemiology and Community Medicine
dc.contributor.supervisorWells, George
dc.contributor.supervisorPerry, Jeffrey
dc.embargo.termsimmediate
dc.degree.nameMSc
dc.degree.levelmasters
dc.degree.disciplineMédecine / Medicine
thesis.degree.nameMSc
thesis.degree.levelMasters
thesis.degree.disciplineMédecine / Medicine
uottawa.departmentÉpidémiologie et médecine sociale / Epidemiology and Community Medicine
CollectionThèses, 2011 - // Theses, 2011 -

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