The Influence of Dynamic Response Characteristics on Traumatic Brain Injury

FieldValue
dc.contributor.authorPost, Andrew
dc.date.accessioned2013-07-22T13:28:20Z
dc.date.available2013-07-22T13:28:20Z
dc.date.created2013
dc.date.issued2013
dc.identifier.urihttp://hdl.handle.net/10393/24333
dc.identifier.urihttp://dx.doi.org/10.20381/ruor-3099
dc.description.abstractResearch into traumatic brain injury (TBI) mechanisms is essential for the development of methods to prevent its occurrence. One of the most common ways to incur a TBI is from falls, especially for the young and very old. The purpose of this thesis was to investigate how the acceleration loading curves influenced the occurrence of different types of TBI, namely: epidural hematoma, subdural hematoma, subarachnoid hemorrhage, and contusion. This investigation was conducted in three parts. The first study conducted reconstructions of 20 TBI cases with varying outcomes using MADYMO, Hybrid III, and finite element methodologies. This study provided a dataset of threshold values for each of the TBI injuries measured in parameters of strain and stress. The results of this study indicated that using a combined reconstructive approach produces results which are in keeping with the literature for TBI. The second study examined how the characteristics of the loading curves which were produced from each reconstruction influenced the outcome using a principal components analysis. It was found that the duration of the event accounted for much of the variance in the results, followed with the acceleration components. Different curve characteristics also accounted for differing amounts of variance in each of the lesion types. Study 3 examined how the dynamic response of the impact influenced where in the brain a subdural hematoma (SDH) could occur. It was found that the largest magnitudes of acceleration produced SDH in the parietal lobe, and the lowest in the occipital lobe. Overall this thesis examined the mechanism of injury for TBI using a large dataset with methodologies which complement each other’s limitations. As a result in depth information of the nature of TBI was attained and information provided which may be used to improve future protection and standard development.
dc.language.isoen
dc.publisherUniversité d'Ottawa / University of Ottawa
dc.subjectTraumatic brain injury
dc.subjectBiomechanics
dc.subjectBrain injury
dc.subjectInjury reconstruction
dc.subjectprincipal component analysis
dc.subjectFalls
dc.subjectFinite element modelling
dc.titleThe Influence of Dynamic Response Characteristics on Traumatic Brain Injury
dc.typeThesis
dc.faculty.departmentSciences de l'activité physique / Human Kinetics
dc.contributor.supervisorHoshizaki, Thomas
dc.embargo.termsimmediate
dc.degree.namePhD
dc.degree.leveldoctorate
dc.degree.disciplineSciences de la santé / Health Sciences
thesis.degree.namePhD
thesis.degree.levelDoctoral
thesis.degree.disciplineSciences de la santé / Health Sciences
uottawa.departmentSciences de l'activité physique / Human Kinetics
CollectionThèses, 2011 - // Theses, 2011 -

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