Bariatric Surgery for Obesity: A Systematic Review and Meta-analysis

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dc.contributor.authorAlobaid, Abdulhakeem M.
dc.date.accessioned2013-05-14T20:30:29Z
dc.date.available2013-05-14T20:30:29Z
dc.date.created2013
dc.date.issued2013
dc.identifier.urihttp://hdl.handle.net/10393/24167
dc.identifier.urihttp://dx.doi.org/10.20381/ruor-3008
dc.description.abstractObesity is the fifth leading cause of global deaths. The efficacy and safety of obesity treatment is still controversial. The objective of the thesis is to evaluate the efficacy and safety of bariatric surgery, through a systematic review of the current evidence and meta- analysis of important outcomes. Nineteen (19) randomized controlled trials (RCTs) with 1346 participants were included. Bariatric surgery resulted in greater weight loss when compared to non-surgical treatment. Weight loss was also associated with resolution and/or improvement of obesity related comorbidites such as diabetes, hypertension, hyperlipidemia, and sleep apnea. Weight loss and safety varied across the surgical procedures. Biliopancreatic diversion/duodenal switch had the greatest weight loss, followed by sleeve gastrectomy and Roux-en-Y gastric bypass, purely restrictive procedures such as vertical banded gastroplasty and adjustable gastric banding resulted in the least weight loss. Long term, high quality, and adequately powered trials are still needed to support the available evidence
dc.language.isoen
dc.publisherUniversité d'Ottawa / University of Ottawa
dc.subjectobesity
dc.subjectmorbid obesity
dc.subjectsurgery
dc.subjectgastric bypass
dc.subjectsleeve gastrectomy
dc.subjectbariatric
dc.subjectgastric banding
dc.subjectanastomosis
dc.subjectRoux-en-Y
dc.subjectbiliopancreatic diversion
dc.subjectduodenal switch
dc.subjectrandomized controlled trials
dc.subjectdiabetes
dc.subjecthypertension
dc.subjecthyperlipidemia
dc.titleBariatric Surgery for Obesity: A Systematic Review and Meta-analysis
dc.typeThesis
dc.faculty.departmentÉpidémiologie et médecine sociale / Epidemiology and Community Medicine
dc.contributor.supervisorWells, George
dc.embargo.termsimmediate
dc.degree.nameMSc
dc.degree.levelmasters
dc.degree.disciplineMédecine / Medicine
thesis.degree.nameMSc
thesis.degree.levelMasters
thesis.degree.disciplineMédecine / Medicine
uottawa.departmentÉpidémiologie et médecine sociale / Epidemiology and Community Medicine
CollectionThèses, 2011 - // Theses, 2011 -

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