Applying Current Methods for Estimating Influenza Burden to an Academic Health Sciences Centre

FieldValue
dc.contributor.authorSmith, Tiffany
dc.date.accessioned2012-08-24T13:07:26Z
dc.date.available2012-08-24T13:07:26Z
dc.date.created2012
dc.date.issued2012
dc.identifier.urihttp://hdl.handle.net/10393/23197
dc.identifier.urihttp://dx.doi.org/10.20381/ruor-5949
dc.description.abstractPublic health planning for influenza is based on morbidity and mortality estimates derived from statistical models. Lower than anticipated 2009 H1N1 pandemic death estimates have raised questions about the method. Examining the statistical method is important for future policy and program development. We compared the main methods of estimating influenza burden through a systematic literature review and by comparing statistical estimates of influenza-attributable burden at the Ottawa Hospital (TOH) to clinical estimates validated through chart review. We identified heterogeneity in methods used to estimate influenza-attributable mortality in the literature which resulted in within-season estimate variation by study. We found statistical estimates of influenza burden at TOH to be 4-8 times greater than clinically validated data. We also found no significant association between the outcomes examined and epidemic periods at TOH. The findings of this study suggest discordance between model estimates by model approach and between model estimates and validated findings. Examining reasons for these discordances should be pursued.
dc.language.isoen
dc.publisherUniversité d'Ottawa / University of Ottawa
dc.subjectInfluenza
dc.subjectMortality
dc.subjectTime Series
dc.subjectPublic Health
dc.subjectInfectious Disease
dc.titleApplying Current Methods for Estimating Influenza Burden to an Academic Health Sciences Centre
dc.typeThesis
dc.faculty.departmentÉpidémiologie et médecine sociale / Epidemiology and Community Medicine
dc.contributor.supervisorForster, Alan
dc.contributor.supervisorWilson, Kumanan
dc.embargo.termsimmediate
dc.degree.nameMSc
dc.degree.levelmasters
dc.degree.disciplineMédecine / Medicine
thesis.degree.nameMSc
thesis.degree.levelMasters
thesis.degree.disciplineMédecine / Medicine
uottawa.departmentÉpidémiologie et médecine sociale / Epidemiology and Community Medicine
CollectionThèses, 2011 - // Theses, 2011 -

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