Focusing-enhanced mixing in microfluidic channels

Description
Title: Focusing-enhanced mixing in microfluidic channels
Authors: Zhang, Zhiyi
Zhao, Ping
Xiao, Gaozhi
Lin, Min
Cao, Xudong
Date: 2008
Abstract: A focusing-based microfluidic mixer was studied. The micromixer utilizes the focusing process required for cytometry to reduce the diffusion distance of molecules to be mixed in order to facilitate the passive diffusion-controlled mixing process. It was found that both the high flow rate ratio of the sheath flow to the flows to be mixed and the low flow rate of the mixing fluids resulted in the short mixing length required within the microfluidic channel. It was shown that a complete mixing was achieved within a distance of 4 mm in the micromixer for the focused mixing fluids at a flow rate of 2 μl/min and a flow rate ratio of the sheath flow to the flows to be mixed at 4:1. The mixer described here is simple and can be easily fabricated and controlled.
URL: http://hdl.handle.net/10393/19663
DOI: 10.1063/1.2894313
CollectionGénie chimique et biologique // Chemical and Biological Engineering
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